開篇用倒敘的關(guān)于法述了湯克（戴苦山?克 Dane Cook 飾）搞砸一次約會白鳥全過程。原他的工作是幫助被友甩掉的男人，替約會前女友并惡心方。這樣女友感念男友好，容易重歸好。不過，湯克最接到的任務(wù)竟然來好友達(dá)斯?。ㄙZ森比格斯 Jason Biggs 飾）。后者追女春秋亞麗西斯（凱特?哈德 Kate Hudson 飾）始終不得赤水，在公司里眼睜看著小白臉親近，卻無計(jì)可施。所，才來找湯克出手兩人約法三章，隨湯克出手，從一起步開始，他就成為亞麗克西斯如影相的伴侶，兩人關(guān)系速升溫，以至于湯都不敢相信，自己經(jīng)離不開這個(gè)女友他覺得困擾，于是經(jīng)驗(yàn)豐富的老爸（歷克?鮑德溫 Alec Baldwin 飾）求教，但是后者文文鼓勵(lì)他鳩占巢，這讓他感到左為難…?
California gold rush, late 1800's: A gun slinging bounty hunter (Mortimer) travels deep into the mountains to find a deadly Apache warrior (Brother Wolf) who is wanted by the law. Along the way he passes through a gold mining Town. The miners help direct Mortimer to the Apache and send him on his way.Mortimer enters the forest and begins to track the Apache. Back in town, the miners un-earth an ancient meteor. They use their pick axes to crack it open. A section of the meteor splits apart and spores explode out of it. The spore surround and infect the entire population of the mining camp. They are transformed into ravenous mutants.After a vicious battle against the Apache warrior, Mortimer exits the forest with his prisoner in shackles. They hike back to the mining town to find them selves surrounded by a horde of blood thirsty mutants. Now Mortimer the gun slinger and Brother Wolf the Warrior must join together to survive the mutant hordes. What ensues is a bloodbath of horror for the Dead and the Damned.
