Eminent Boston Psychiatrist, Frasier Crane, last seen gracing the bars of Cheers has left his life there to start afresh in Seattle. He now has a spot as a popular radio Psychiatrist, giving him the chance to spread words of wit and wisdom to the masses. He shares his apartment with his retired cop father, Martin, and his father's physical care assistant, Daphne Moon. Add in brother Niles, Eddie the dog, some bizarre situations and plenty of humour and you've got all the ingredients for an excellent show and worthy successor to Cheers.
吉爾（史蒂夫·馬丁 Steve Martin 飾）最小的兒子凱文（Jasen Fisher 飾）因為性格極度內向而被學老師勸退回到了家中這可急壞了吉爾。為幫助凱文重拾自信，爾天天陪著凱文玩耍戲，但似乎沒有什么果。吉爾的妹夫內森里克·莫拉尼斯 Rick Moranis 飾）的教育理念和吉爾完全相反淑士他希望夠將女兒培養(yǎng)成為一有用之才，可在他的鴨式教育的壓迫之下不僅女兒失去了快樂生活，就連妻子也最離開了他。 巴克（瑪麗·斯汀伯根 Mary Steenburgen 飾）是一名單親母親，獨自撫著一雙兒女，生活本不易的她還遭遇了兩孩子的叛逆期，女兒早結婚成家，兒子則益沉默寡言?
